4-[2-(4-methylpiperazin-1-yl)ethyl]aniline

4-[2-(4-methylpiperazin-1-yl)ethyl]aniline - Names and Identifiers

Name	4-[2-(4-methylpiperazin-1-yl)ethyl]aniline
Synonyms	LogP OTAVA-BB 1036666 4-(2-(4-methylpiperazin-1-yl)ethyl)aniline 4-[2-(4-Methyl-1-piperazinyl)ethyl]aniline 4-[2-(4-Methylpiperazin-1-yl)ethyl]aniline 4-[2-(4-methylpiperazin-1-yl)ethyl]aniline [4-[2-(4-METHYLPIPERAZIN-1-YL)ETHYL]PHENYL]AMINE benzenamine, 4-[2-(4-methyl-1-piperazinyl)ethyl]- Benzenamine, 4-[2-(4-methyl-1-piperazinyl)ethyl]-
CAS	262368-48-9
InChI	InChI=1/C13H21N3/c1-15-8-10-16(11-9-15)7-6-12-2-4-13(14)5-3-12/h2-5H,6-11,14H2,1H3

4-[2-(4-methylpiperazin-1-yl)ethyl]aniline - Physico-chemical Properties

Molecular Formula	C13H21N3
Molar Mass	219.33
Density	1.048g/cm³
Boling Point	353.8°C at 760 mmHg
Flash Point	165.3°C
Vapor Presure	3.51E-05mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.567

4-[2-(4-methylpiperazin-1-yl)ethyl]aniline - Introduction

4-[2-(4-methylpiperazin-1-yl)ethyl]aniline is an organic compound with the chemical formula C15H22N2. It is a compound with an aniline structure and a methylpiperazinyl substituent.

Nature:
-Appearance: 4-[2-(4-methylpiperazin-1-yl)ethyl]aniline is a colorless to light yellow solid.
-Melting point: about 68-72 ° C.
-Solubility: It is easily soluble in common organic solvents (such as ethanol, dimethylformamide and dichloromethane).
-Stability: It is relatively stable under regular conditions.

Use:
-This compound is often used as an intermediate in pharmaceutical research and for the synthesis of other compounds.
-It can also be used in the synthesis of heterocyclic compounds, nitrogen-containing compounds and other organic synthesis reactions.

Method:
4-[2-(4-methylpiperazin-1-yl)ethyl]aniline can be synthesized by the following methods:
First, 4-methylpiperazine is reacted with bromoethane to obtain 2-(4-methylpiperazinyl) ethyl bromide. This bromide is then reacted with aniline over the appropriate conditions and catalyst to give 4-[2-(4-methylpiperazin-1-yl)ethyl]aniline.

Safety Information:
- 4-[2-(4-methylpiperazin-1-yl)ethyl]aniline is generally considered safe under reasonable use and storage conditions, but the following matters still need to be paid attention:
-Use with appropriate personal protective equipment, such as gloves and goggles.
-Avoid contact with skin and inhalation of its dust.
-Avoid eating or exposing it to mucosal areas such as the mouth and eyes.
-During use, storage and handling, please follow the correct laboratory safety procedures and relevant regulations.

Please note that the above information is for reference only. The specific experimental conditions, use and safety evaluation should be based on the actual situation and the regulatory requirements of the region.

Last Update：2024-04-09 21:01:54